Stainless Steel Centrifuges

CIP and SIP-able Systems

CIP and SIP Stainless Steel Systems

Our reliable and robust stainless steel equipment addresses even the most challenging separations. Leading biopharmaceutical companies around the world rely on our machines to manufacture their licensed products. Clean-in-Place (CIP) and Sterilize-in-Place (SIP) systems can be used during product or batch changes to prevent contamination.

Powerfuge Family

  • Designed for bacteria, fungi, proteins and sub-micron particles
  • Proven for the production of plasmid DNA, vaccines, plasma protein, cellular agriculture and specialty chemicals
  • G-forces up to 20,000 x g, the highest g force in the market
  • Bowl volumes from 1.1 L to 36 L
  • Flow rate from 250 ml/min to 1700 L/hr
  • Solid-bowl centrifuges
  • Automatic solid discharge
  • SIP/CIP capabilities
  • Hazardous duty option available

Viafuge Family

  • Designed for mammalian, insect and plant cells
  • Typical cell viability of 98% or higher
  • Yield up to 98%
  • G-forces up to 10,000 x g
  • Bowl volumes from 1.4 L to 16.7 L
  • Flow rate 2,400 L/hr
  • Solid-bowl centrifuges
  • Automatic centrate discharge
  • SIP/CIP capabilities

Key Features

Advantages of Our Equipment

Our long history and deep expertise with pioneering separation technology allows us to deliver top-performing solutions through a reliable supply chain.

Performance

Our reliable and robust centrifuges address even the most challenging separations.

Scalability

Our equipment accommodates small process development volumes to very large commercial needs, allowing for seamless scale-up and scale-down.

Versatility

Our stainless steel centrifuges are designed to serve a variety of markets.

Stainless Steel Centrifuges

The Powerfuge® Family

Powerfuge centrifuges are well suited for separation of bacteria, fungi, proteins, and sub-micron particles. At the end of a run, compressed solids can be removed with minimal time and effort.

Powerfuge P18

May 18, 2023, 11:16
Title : Powerfuge P18
Heading : Powerfuge P18
Listing description : Boasting the highest capacity in the scalable Powerfuge family, with a 36 L bowl, the P18 System has a flow rate up to 600 L/hr for batches of up to 2,000 L.
Order : 4

Clean-in-Place / Sterilize-in-Place System

The Powerfuge P18 is a batch liquid/solid separation system for bacteria, yeast, proteins and sub-micron particles. This industrial centrifuge provides continuous-flow two-phase separation of solids and liquids, and meets cGMP requirements as well as chemical and pharmaceutical industry protocols.

  • Bowl capacity: 36 L
  • Flow rates up to 600 L/hr for batches up to 2,000 L
  • Footprint ~ 178 cm wide x 165 cm deep x 246 cm high (70” x 65” x 97”)
  • Total weight ~ 2948 kg (6,500 lbs)
  • Fully scalable to smaller automated Pilot, P6 and P12 models
  • Drier solids, clearer centrates
Performance

With g forces up to 20,000 X g, the Powerfuge addresses even the most challenging separations.

Scalability

The Powerfuge family of products can be used for small process development volumes all the way to very large commercial manufacturing, allowing for seamless scale-up and scale-down.

Versatility

The Powerfuge is designed to serve the needs of a variety of markets.

Features
  • Bowl capacity: 36 L
  • Flow rates up to 600 L/hr for batches up to 2,000 L
  • Variable speeds up to 20,000 x g
  • Sealed automatic operation
  • Full CIP/SIP designs: automated CIP/SIP cycles can be performed via the PLC-controlled operating sequence.
  • cGMP construction
  • Designs available for ASME-rated boundary, hazardous locations, and aseptic operations
  • Continuous flow two-phase separation
  • Optional hazardous duty (Class 1, Div 1) CE configurations are available
  • State-of-the-art manufacturing facility located in Clearwater, Florida USA
How It Works

Using an innovative design, the feed is introduced through a stationary pipe and accelerated to full rotational speed before entering the titanium-alloy bowl. In this system, centrifugal forces as great as 20,000 x g permit separation of even sub-micron particles. Compressed solids are periodically removed with a fully-automated scraping cycle. After the solids have been discharged, automated CIP/SIP cycles can be performed via the PLC-controlled operating sequence.

Automation and General Specifications
  • Allen-Bradley® or Siemens® PLC
  • Allen-Bradley or Siemens HMI touchscreen 30.7 cm (12.1”)
  • Maximum case pressure (for cooling) 6.9 bar (100 psi)
Utility Requirements
  • Power configuration: Single phase voltage supply:
    • US: 460V/60 Hz, 60 A
    • Europe: 400V/50 Hz, 60 A
    • Japan: 200V/60 Hz/50 Hz, 120 A
  • Optional: Others as needed
  • Pneumatic: Clean, dry air supply 6 bar (90 psi) at 566 SLPM (20 SCFM)
Process Wetted Parts Construction
  • 316L Stainless Steel
  • 17-4 PH Stainless Steel
  • Nitronic 60 Stainless Steel
  • Platinum-cured silicone hoses
  • EPDM elastomers
  • Ti-6Al-4V Titanium
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Stainless Steel Centrifuges

The Viafuge® Family

The Viafuge centrifuges are low-shear stainless steel systems designed for separation of mammalian, insect and plant cells with typical cell viability of 98% or higher.

Powerfuge P18

May 18, 2023, 11:16
Title : Powerfuge P18
Heading : Powerfuge P18
Listing description : Boasting the highest capacity in the scalable Powerfuge family, with a 36 L bowl, the P18 System has a flow rate up to 600 L/hr for batches of up to 2,000 L.
Order : 4

Clean-in-Place / Sterilize-in-Place System

The Powerfuge P18 is a batch liquid/solid separation system for bacteria, yeast, proteins and sub-micron particles. This industrial centrifuge provides continuous-flow two-phase separation of solids and liquids, and meets cGMP requirements as well as chemical and pharmaceutical industry protocols.

  • Bowl capacity: 36 L
  • Flow rates up to 600 L/hr for batches up to 2,000 L
  • Footprint ~ 178 cm wide x 165 cm deep x 246 cm high (70” x 65” x 97”)
  • Total weight ~ 2948 kg (6,500 lbs)
  • Fully scalable to smaller automated Pilot, P6 and P12 models
  • Drier solids, clearer centrates
Performance

With g forces up to 20,000 X g, the Powerfuge addresses even the most challenging separations.

Scalability

The Powerfuge family of products can be used for small process development volumes all the way to very large commercial manufacturing, allowing for seamless scale-up and scale-down.

Versatility

The Powerfuge is designed to serve the needs of a variety of markets.

Features
  • Bowl capacity: 36 L
  • Flow rates up to 600 L/hr for batches up to 2,000 L
  • Variable speeds up to 20,000 x g
  • Sealed automatic operation
  • Full CIP/SIP designs: automated CIP/SIP cycles can be performed via the PLC-controlled operating sequence.
  • cGMP construction
  • Designs available for ASME-rated boundary, hazardous locations, and aseptic operations
  • Continuous flow two-phase separation
  • Optional hazardous duty (Class 1, Div 1) CE configurations are available
  • State-of-the-art manufacturing facility located in Clearwater, Florida USA
How It Works

Using an innovative design, the feed is introduced through a stationary pipe and accelerated to full rotational speed before entering the titanium-alloy bowl. In this system, centrifugal forces as great as 20,000 x g permit separation of even sub-micron particles. Compressed solids are periodically removed with a fully-automated scraping cycle. After the solids have been discharged, automated CIP/SIP cycles can be performed via the PLC-controlled operating sequence.

Automation and General Specifications
  • Allen-Bradley® or Siemens® PLC
  • Allen-Bradley or Siemens HMI touchscreen 30.7 cm (12.1”)
  • Maximum case pressure (for cooling) 6.9 bar (100 psi)
Utility Requirements
  • Power configuration: Single phase voltage supply:
    • US: 460V/60 Hz, 60 A
    • Europe: 400V/50 Hz, 60 A
    • Japan: 200V/60 Hz/50 Hz, 120 A
  • Optional: Others as needed
  • Pneumatic: Clean, dry air supply 6 bar (90 psi) at 566 SLPM (20 SCFM)
Process Wetted Parts Construction
  • 316L Stainless Steel
  • 17-4 PH Stainless Steel
  • Nitronic 60 Stainless Steel
  • Platinum-cured silicone hoses
  • EPDM elastomers
  • Ti-6Al-4V Titanium
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