Powerfuge P12

Product Overview

Clean-in-Place / Sterilize-in-Place System

The Powerfuge P12 System is a batch liquid/solid separation system for bacteria, yeast, proteins and sub-micron particles. It is designed to provide continuous-flow two-phase separation of solids and liquids and meets cGMP and CE requirements as well as chemical and pharmaceutical industry protocols.

  • Bowl capacity: 8L
  • Flow rates up to 500 L/hr for batches up to 500 L
  • Footprint ~ 78.7 cm wide x 172.7 cm deep x 203.2 cm high (31” x 68” x 80”)
  • Total weight ~ 1924 kg (4,240 lbs)
  • Fully scalable to smaller automated Pilot and P6 models
  • Fully scalable to larger automated P18 model
  • Drier solids and clear liquids

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With g forces up to 20,000 X g, the Powerfuge addresses even the most challenging separations.


The Powerfuge family of products can be used for small process development volumes all the way to very large commercial manufacturing, allowing for seamless scale-up and scale-down.


The Powerfuge is designed to serve the needs of a variety of markets.

  • Bowl capacity: 8 L
  • Flow rates up to 500 L/hr for batches up to 500 L
  • Variable speeds up to 20,000 g
  • Sealed automatic operation
  • Full CIP/SIP designs + automated CIP/SIP cycles
  • Meets cGMP and CE requirements
  • Designs available for ASME-rated boundary, hazardous locations, and aseptic operations
  • Continuous-flow two-phase separation
  • Optional hazardous duty (Class 1, Div 1) CE configurations are available
  • State-of-the-art manufacturing facility located in Clearwater, Florida USA
How It Works

Using an innovative design, the feed is introduced through a stationary pipe and accelerated to full rotational speed before entering the titanium-alloy bowl. In this system, centrifugal forces as 20,000 g permit separation of even sub-micron particles. Compressed solids are periodically removed with a fully automated scraping cycle. After the solids have been discharged, automated CIP/SIP cycles can be performed via the PLC-controlled operating sequence.

Automation and General Specifications
  • Allen-Bradley® or Siemens® PLC
  • Allen-Bradley or Siemens HMI touchscreen 30.7 cm (12.1”)
  • Maximum case pressure (for cooling) 6.9 bar (100 psi)
Utility Requirements
  • Power configuration: Single phase voltage supply:
    • US: 460V/60 Hz, 45 A
    • Europe: 400V/50 Hz, 46 A
    • Japan: 200V/60 Hz/50 Hz, 90 A
  • Optional: Others as needed
  • Pneumatic: Clean, dry air supply 6 bar (90 psi) at 566 SLPM (20 SCFM)
Process Wetted Parts Construction
  • 316L Stainless Steel
  • 17-4 PH Stainless Steel
  • Nitronic 60 Stainless Steel
  • Platinum-cured silicone hoses
  • EPDM elastomers
  • Ti-6Al-4V Titanium


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