The Viafuge® V12 is designed for fast, gentle medium- to large-scale cell harvesting and clarification. Capable of separating a wide variety of mammalian and insect cells with little to no damage, the Viafuge V12 offers high purity results with undetectable cell concentrations in clarified supernatant.
The Viafuge V12’s unique design minimizes shear forces on cells, boasting a typical cell viability of 98% or higher and up to 98% yield.
Processes developed on the Viafuge® Pilot can be seamlessly scaled to the Viafuge V12.
Using an innovative design, the Viafuge V12 introduces feed through a stationary pipe, where it is accelerated to full rotational speed under low shear before entering the titanium-alloy bowl. Cells are then concentrated along a gentle path between the core and the bowl wall. The clarified supernatant is continuously discharged by gravity at atmospheric pressure. Periodically, the concentrated cells are automatically recovered from the Viafuge V12 for collection, and the cycle is repeated to process the remainder of the feed batch.
“The UniFuge was easy to scale-up, and the Viafuge enables us to recover viable cells at large scale, beyond what single-use can typically accomplish."
Cellular Agriculture Entrepreneur
Animal Vaccine Manufacturing Operations Manager
Director of Operations, Vaccine Manufacturing
Senior Process Development Scientist, pDNA
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Associate Director of Vaccine Franchise
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