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Viafuge® Product Family
Viafuge® Pilot
Stainless Steel Centrifuges
Viafuge® Pilot Stainless Steel Centrifugation
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Product overview

Clean-in-Place / Sterilize-in-Place System

The Viafuge Pilot is designed for fast, gentle, small- to medium-scale cell harvesting and supernatant clarification. Capable of separating a wide variety of mammalian and insect cells with little to no damage, the Viafuge Pilot offers high purity results with undetectable cell concentrations in clarified supernatant.
  • Bowl capacity: 1.4 L
  • Flow rates up to 240 L/hr for batches up to 500 L
  • Footprint:
    • Centrifuge: 5.5 cm wide x 8.3 cm deep x 11.8 cm high ( 14” x 21” x 30”)
    • Cabinet: 6.3 cm wide x 6.3 cm deep x 11.8 cm high (16” x 16” x 30”)
  • Total weight ~ 136 kg (300 lbs)
  • Fully scalable to larger automated V12 models
  • Gentle cell harvesting and supernatant recovery
  • Improved product processing
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Low-Shear Performance
The Viafuge Pilot’s unique design minimizes shear forces on cells, boasting a typical cell viability of 98% or higher and up to 98% yield.
Scalability
Processes developed on the Viafuge Pilot can be seamlessly scaled to the Viafuge V12.
Features
  • Bowl capacity: 1.4L
  • Flow rates up to 240 L/hr for batches up to 500 L
  • Variable speeds up to 10,000 x g
  • SIP optional
  • cGMP construction
  • ASME-rated designs available
  • Low-shear design
  • Flexible optimization
  • Optional Hazardous Duty (Class 1, Div 1, Group C and D)  and CE configurations are available
  • State-of-the-art manufacturing facility located in the United States
How It Works
Cells are concentrated at the bowl wall while clarified supernatant is continuously discharged throughout the separation process. Once the bowl fills with cell concentrate, a simple manifold system and concentrate pump is used to recover the cells without breaking containment. Subsequent cycles are performed for recovery of larger batch sizes
Automation and General Specifications
  • Allen Bradley® or Siemens® PLC
  • Allen Bradley® or Siemens® HMI touchscreen 30.7 cm (12.1”)
  • Maximum case pressure (for cooling) 6.9 bar (100 psi)
Utility Requirements
  • Power configuration: Three phase voltage supply:
    • US: 230V/60 Hz, 20 A
    • Europe: 200V/50 Hz, 20 A
    • Japan: 200V/60 Hz/50 Hz, 20 A
  • Optional: Others as needed
  • Pneumatic: Clean, dry air supply 6 bar (90 psi) at 1 SLPM
Process Wetted Parts Construction
  • USP Class VI components
    • 316L Stainless Steel
    • 17-4 PH Stainless Steel
    • Nitronic 60 Stainless Steel
    • Platinum cured silicone hoses
    • EPDM elastomers
    • Ti-6Al-4V Titanium

Endorsements

See What People Are Saying About Our Equipment
“The UniFuge was easy to scale-up, and the Viafuge enables us to recover viable cells at large scale, beyond what single-use can typically accomplish.”

Cellular Agriculture Entrepreneur

“We replaced our bottle centrifuges with a single continuous Viafuge, saving cleaning, autoclaving, and manual manipulations."

Animal Vaccine Manufacturing Operations Manager

“Gentle handling of our cells at scale resulted in higher VLP recovery.”

Director of Operations, Vaccine Manufacturing

“The high g-force of the Powerfuge [e. Coli lysate clarification] reduced our downstream clarification needs.”

Senior Process Development Scientist, pDNA

“Removing large particles with Powerfuge reduced the number of filtration steps.”

Manufacturing Engineer, Pigments

“The Powerfuge closed up our ethanol process and its automatic scraping improved our recovery.”

Associate Director of Vaccine Franchise

“The explosion proof Powerfuge closed up our solvent process for a safe and environmentally friendly manufacturing method.”

Senior Process Engineer, Pigments